Stem Cells, Radial Glial Cells, and a Unified Origin of Brain Tumors

Stem cells, radial glial cells, and a unified origin of brain tumors.

Stem cells and the origin and propagation of brain tumors.

In recent years there has been a flood of interest in the relationship between brain tumors and stem cells. Some investigators have focused on the sensitivity of normal stem cells to transformation, others have described phenotypic or functional similarities between tumor cells and stem cells, and still others have suggested that tumors contain a subpopulation of ;;cancer stem cells'' that is c...

P10: Reactive Glial Cells for Brain Injury

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p10: reactive glial cells for brain injury

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

Title: Cancer Stem Cells and Brain Tumors

Besides the role that normal stem cells play in organogenesis, cancer stem cells are thought to be crucial for tumorigenesis. Most current research on human tumors is focused on the molecular and cellular analysis of the bulk tumor mass. However, evidence in leukemia and, more recently, in solid tumors suggests that the tumor cell population is heterogeneous. During the last years, several grou...